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R&D 100 Awards

Agilent Receives Prestigious R&D 100 Award for Technical Innovation PicoTRECT Opens New Avenues of Research for Atomic Force Microscopy (AFM) Recognized as One of the 100 Most Technologically Significant Products of the Year

Agilent is an R&D 100 Awards winner for its new PicoTREC. The awards are sponsored by R&D Magazine and recognize the top 100 products introduced into the marketplace during the year. PicoTREC is the only commercially available instrument to add real-time� simultaneous Topography and RECognition imaging capability to the atomic force microscope (AFM). A breakthrough tool for AFM� PicoTREC allows researchers to pursue new avenues of discovery in all areas of nanotechnology and nanoscience.

PicoTREC� used together with Agilent's 5 series? SPM (Scanning Probe Microscope) and MAC Mode?� represents a new product category for AFM. PicoTREC improves the speed� sensitivity� and accuracy of recognition and adhesion studies at the molecular level. Therefore� it can be used to greatly accelerate existing research and to perform experiments that were not possible before. It is a label-less detection methodology so sensitive samples are not changed by the introduction of radioactive� fluorescent� and other markers. Furthermore� single molecule sensitivity is not only possible� with PicoTREC it is routine.

PicoTREC creates new possibilities for using AFM in life science� materials science� electrochemistry and other fields. For example� PicoTREC offers researchers in cell biology� nanobiotechnology and pharmacology the ability to explore dynamic properties of molecular binding events. It enables studies on a host of ligand-receptor interactions including membranes� cells� antibody-antigen� drug-receptor� DNA-protein� DNA-DNA� and smart materials. In addition� for scientists studying the characteristics of data storage media including CD's� DVD's and hard drives� or sensors� polymers and other materials� PicoTREC provides a better understanding of the molecular level structures and interactions that influence their behaviors.

Picotrec获得美国R&D 100 Awards 大奖�

主要特点９�/strong>

安捷伦的PicoTREC分子识别功能能应用到我们每个AFM型号中，它通过探测两种物质的分子键是否发生相互结合，来快速识别感兴趣的官能团，轻松取代其它供货商的那些虽可获得同样结果，但却既耗时又操作复杂，且只能借助力谱测量等分析的功能块。生物活体成像模式与PicoTREC结合使用，通过分析分子键和表面的吸附力，你可研究生物系统的动态性质，包括抗体—抗原、配体—受体、药物－受体、DNA—蛋白质、DNA—DNA等等�

概述

简便快速的识别出分子结合事件中的分子或发生区域

通过结合相互作用来示出物质的种类

给出样品表面的吸附性的分布

提高得结果的速度、准度和精度

通过确定分子作用区来加速力测试

图示出分子的排列

仪器特点

无标记监测分子结合事�

同时获取形貌像和分子识别�

实时监测样品表面的结合事件和粘附性能

与安捷伦科技的生物活体成像模式和5500系列完全兼容

应用领域�

1、探索生物领域的动态性能(抗体-抗原，配�?受体� 药物-受体� DNA-蛋白质， DNA-DNA �?，分子结合研穵�

2、排列检测应�

3、显示表面分子结合事件和粘附性的状况

4、更多需要探索的未知领域